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Figure 1 Mean (±SE) change in FMD after four months of therapy in the three treatment groups: placebo group (n = 25); folic acid only group (n = 25); and folic acid plus antioxidants group (n = 25) (p = 0.036 for overall comparison of the three groups). Compared with placebo, folic acid alone significantly improved FMD after four months (p = 0.04). In contrast, the improvement in the folic acid plus antioxidants group was not significantly different from that in the placebo group (p = 0.45) or the folic acid only group (p > 0.5).
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