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Figure 4 Top: Receiver operating curve (A) for the optimal level of VE reduction demonstrating clearly that a 2 cm/s decrease has the best level of discrimination. Receiver operating curve (B) for the diagnostic accuracy of stress induced VE reduction in relation to incremental angiographic luminal narrowing. Optimal discrimination is at  50% stenosis. Bottom (C): Receiver operating curve comparing the three noninvasive imaging modalities during stress tests each with reference to incremental angiographic luminal narrowing. Pulsed Doppler myocardial mapping has the highest discriminatory power with 0.90 area under the curve (12) as compared with 0.77 in two-dimensional echocardiography and 0.81 in SPECT. A 50% angiographic stenosis yields the optimal discriminatory power for PMD and stress echocardiography and a 75% luminal narrowing for SPECT. Doppler = PMD; PMD = pulsed Doppler myocardial mapping; SPECT = perfusion scintigraphy; 2D Echo = two-dimensional echocardiography.
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