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Figure 5 Intravascular ultrasound image of a calcified coronary artery (left), and the relative weights of calcium salts (top) and total cholesterol (bottom) in the same artery plane determined by Raman spectroscopy. The IVUS images were obtained from an intact artery segment, which were marked by a needle (12 o’clock). Raman spectra were obtained from the artery after the artery was opened. The IVUS image shows a calcification, in agreement with the calcium salts detected with Raman spectroscopy. Cholesterol was detected with Raman spectroscopy but could not be discriminated within the IVUS image (with courtesy of R Buschman and TJ Römer, Leiden University Medical Center).
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