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Figure 3 Magnetic resonance imaging of abdominal aorta (arrow) in normal mouse and apoE-KO mouse showing differences between normal and atherosclerotic arteries. On all MRIs, lumen is dark. Normal abdominal aorta wall thickness is approximately 50 µm and was not clearly visible at spatial in plane resolution of 97 µm. Wild-type mice were free of atherosclerotic lesions as shown on MRIs in A and B and histopathology (C). Large atherosclerotic lesion (arrow) that encircles the abdominal aorta of an apoE-KO mouse is shown on the MRI in D and E and was confirmed by histopathologic study (F). All MRIs have pixel size of 97 x 97 x 500 µm3 (adapted from Fayad et al [50]).





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