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Figure 2 Representative example of ergonovine echocardiography (A and B) and invasive spasm provocation testing during diagnostic coronary angiography (C and D) in a 47-year-old man. Left ventricular wall motion at end-systole recorded in the apical two-chamber view was demonstrated (A and B). Compared with the basal status (A), prominent loss of systolic myocardial thickening in the inferior wall developed with an ergonovine dose of 0.15 mg (B, white arrow), which was compatible with myocardial ischemia due to coronary artery spasm in the right coronary artery territory. Coronary angiogram taken three days later revealed no significant fixed disease. Intravenous injection of ergonovine (E1) provoked total occlusion of the distal right coronary artery (C), and the angiogram after injection of nitroglycerin (N) showed completely normal right coronary artery and relief of total occlusion (D).
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