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Figure 3 Effects of bradykinin (BK) and acetylcholine (ACh) on coronary blood flow in eight transplant patients with and eight without allograft rejection (grades 2 and 3 of the ISHLT classification). Rejection did not impair the dose-dependent increase in coronary blood flow induced by bradykinin. On the contrary, the acetylcholine-induced increase in coronary blood flow was significantly lower (*p < 0.05) in the presence of rejection. Open circles = no rejection; black circles = rejection.
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