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Figure 7 Peak calcium current in cardiac myocytes. The cells were incubated with 10 ng/ml IL-1ß (IL) in the presence or absence of 10–7 mol/liter KT5823, 5 x 10–4 mol/liter aminoguanidine (AG), and 3 mmol/liter NG-monomethyl-L-arginine (L-NMMA), 10–3 mol/liter 8-bromo cGMP in the presence or absence of 10–7 mol/liter KT5823, or 10–3 mol/liter sodium nitroprusside (SNP) for 48 h, and calcium current (ICa) was measured as described in Methods. §p < 0.0001 vs. control; #p < 0.01 vs. 8-bromo-cGMP (n = 13).





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