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Figure 1 Time course of NO2–/NO3– (NOx) production. Cardiac myocytes were incubated with either (a) 10–4 mol/liter or 10–3 mol/liter sodium nitroprusside (SNP), or (b) 10 ng/ml IL-1ß (IL) in the presence or absence of 3 mmol/liter NG-monomethyl-L-arginine (L-NMMA) for the indicated time, and NOx production in the culture media was measured as described in Methods. Control preparations contained no additives. The interaction between five groups and time course was significant (p < 0.0001).  p < 0.0001 vs. control (n = 6).
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