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Figure 4 Top graphs = mortality reduction on amiodarone in patients with depressed HRV. For each patient category and for each dichotomy of HRV, the graphs show the mortality reduction on amiodarone during the follow-up of EMIAT, that is, the value ([mortality on placebo] – [mortality on amiodarone])/[mortality on placebo], in patients with HRV  the given dichotomy. Bottom graphs = statistical significance of the difference between survival on placebo and survival on amiodarone in groups of patients selected in the same way (the vertical axes show the l/p values—the higher the more significant; the statistical significance p = 0.05 corresponds to the value of 20 on the vertical axes). Note that the ranges of horizontal axes of graphs for both HRV index and standard deviation of normal to normal intervals correspond approximately to the range of 10% to 40% of the population of the study. arrhythmia = arrhythmia signs on Holter (see the text for details); BB = beta-blockers; fast HR = baseline short-term heart rate  75 beats/min; HRV = heart rate variability; low LVEF = left ventricular ejection fraction 30%; MI = myocardial infarction. Solid line = all patients; open square = first MI; solid square = on beta-blockers; open triangle = low LVEF; open diamond = arrhythmia; Ex = fast heart rate.
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