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Figure 5 Odds ratio and 95% CI for risk of ischemic heart disease as a function of apolipoprotein E genotype relative to the common  33 genotype as the reference in premenopausal women (n = 1,451), untreated postmenopausal women (n = 2,908) and in HRT treated postmenopausal women (n = 689). Logistic regression models adjusted for 10 year age groups. The size of the squares reflects the number of individuals with each genotype. The 22 genotype in premenopausal women and the 22, 42 and 44 genotypes in HRT treated postmenopausal women were too few to calculate reasonable odds ratios. CI = confidence interval; HRT = hormone replacement therapy.
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