Please click here to obtain permission to reproduce this image.
Click on image to view larger version.
Figure 2 Brief representation of possible mode of action of PDGF on SMC leading to restenosis. Numbers in parentheses indicate sites of action of various anti-PDGF drugs, as listed in Table 1. (Note: because this is only a schematic representation, it is not possible to show the site of action of all the drugs listed in Table 1.) 1,2-DG = 1,2-diacylglycerol; IP3 = inositol triphosphate; PKC = protein kinase C; PTK = protein tyrosine kinase.
|
