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Figure 1 Diastolic aortic pressure during CPR. Repeated doses of vasopressin (line with diamonds) but not epinephrine (line with squares) or saline placebo (line with triangles) maintained the mean value ±SEM of aortic diastolic blood pressure above a threshold of ~30 to 40 mm Hg (horizontal dashed lines), which makes successful defibrillation likely. *p < 0.05 vs. epinephrine and saline placebo. §p < 0.05 vs. saline placebo. ACLS = advanced cardiac life support; BLS = basic life support; DA 1 = drug administration of 0.4 U/kg vasopressin vs. 45 µg/kg epinephrine vs. saline placebo; DA 2 = drug administration of 0.4 U/kg vasopressin vs. 45 µg/kg epinephrine vs. saline placebo; DA 3 = drug administration of 0.8 U/kg vasopressin vs. 200 µg/kg epinephrine vs. saline placebo. VF = ventricular fibrillation. Time is given in minutes (') and seconds ('').





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