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Figure 5 Top panel: The effects of aortic constriction on the mean multibeat PRSW measurements (Vw and Mw) and single-beat Mw (SBMw) estimates in Group II dogs. Neither multibeat nor single-beat estimates are sensitive to the increased afterload. There were no significant differences between multibeat and single beat Mw values, whether based on individual k values (measured) or a constant k value of 0.7 (calculated). Bottom panel: The corresponding volume-axis intercept (Vo) and slope (Ees) of the ESPVR, single-beat Ees (SBEes) and PWRmax/EDV2 data (see text). ESPVR = end-systolic pressure-volume relationship; Mw = slope of the PRSW relationship; PRSW = preload recruitable stroke work; PWRmax/EDV2 = maximum left ventricular power divided by the square of end-diastolic volume. Vw = volume-axis intercept of the PRSW relationship. *p < 0.05 vs. control.
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