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Figure 3 Top panel: Relationship between stroke work calculated as the product of stroke volume and mean ejection pressure and stroke work calculated as pressure-volume loop area based on the same beats from Group I dogs displayed in the middle panel. Middle panel: Relationship between single beat Mw (SBMw) estimates and multibeat Mw measurements in Group I. Multibeat data were obtained during vena caval occlusions performed before and during aortic constriction. Single beat estimates were made from the first steady-state beat preceding each vena caval occlusion. The relationships were not significantly different from the line of identity, whether based on individual measured k values (SBMw,measured, open circles) or calculated assuming k to be constant at 0.7 (SBMw,calculated, closed circles). Bottom panel: Bland-Altman analysis (25) of the same calculated SBMw and multibeat Mw values: the difference between multibeat Mw and SBMw values is plotted against their average. Mw = slope of the PRSW relationship.
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