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Figure 2 Time course changes in hemodynamic parameters recorded at intervals of 1 min from the control to the end of final inflation. Upper panel: SBP significantly decreased 120 s after the administration of nicorandil or ISDN. Middle panel: DBP significantly decreased 120 s after the administration of nicorandil and significantly decreased only immediately after the administration of ISDN. Lower panel: HR did not alter throughout the experiment in all the groups. DBP = diastolic blood pressure; HR = heart rate; ISDN = isosorbide dinitrate; SBP = systolic blood pressure.
