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Figure 2 Effect of 5HT on VSMC preincubated with LDL. Synchronized VSMCs were stimulated without or with different concentrations of LDL. After 24 h of incubation, indicated concentration of 5HT was added and incubated for an additional 24 h. One hundred percent equals the baseline value for 3H-thymidine incorporation into DNA (254 ± 21 cpm). Values shown are mean ± standard error. 5HT = serotonin. All other abbreviations as in Figure 1. n = 24; *p < 0.01 compared with corresponding control; **p < 0.01 compared with corresponding lipoprotein group.
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