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Figure 5 Adenylyl cyclase activity in rat pulmonary membrane preparations was determined in lungs from animals with CHF 28 days after aortic banding (n = 7; hatched bars) and sham-operated controls (n = 7; open bars). Enzyme activity was measured under basal conditions and during stimulation with isoproterenol (Iso, 0.1 mmol/liter), sodium fluoride (NaF, 10 mmol/liter) or forskolin (Fors, 0.1 mmol/liter). Total lung membrane protein concentration was unchanged after aortic banding (see Results section). Mean ± SEM. *p 0.05 (two-tailed t test).
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