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Figure 3 Pedigree of OHSU FDC-3. FDC-3 is a very large African-American family spanning eight generations with 481 living relatives who are related to the index patient by her maternal grandfather. All members of generations I and II are deceased and only four members of generation III are living. FDC-3 has a broad geographic distribution with most of the family residing in the midwestern and southern U.S., and a small portion reside in the Pacific Northwest. Numbers below the subject symbols and numbers in parentheses, i.e. (#10), denote the number of known descendants and the number of screened subjects, respectively, not shown due to space limitations.





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