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Figure 5 Sequence of micrographs showing the process of attachment of fluorescently labeled QW7437 microbubbles to the postcapillary venules. The flow is from top to bottom right. A: A 12-µm postcapillary venule indicated by an arrow running on the right side of a 48-µm collecting venule under transillumination. B: Two microbubbles showed transient stoppage to a 12-µm postcapillary venule 150 s after the labeled QW7437 bolus injection. C: 1.0 s after B. The right microbubble (small arrow) moved as slowly as 15 µm in 1.0 s; however, the left microbubble (large arrow) remained at the same site. D: 5.0 s after B. The right microbubble (small arrow) moved away after stopping for 4.0 s at the same locale shown in C. The left microbubble (large arrow) stayed at the same site as shown in B. E: 5.07 s after B. The microbubble. (large arrow) has started to move again after stopping for 5.1 s.
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