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Figure 1 Study design. One hundred twenty-five patients were randomized in a 1:1:1 ratio to heparin, low-dose argatroban and high-dose argatroban therapy. Heparin was administered as a bolus of 70 U/kg over 1 min followed by an infusion of 15 U/kg/h. A bolus of 100 µg/kg of argatroban was given over 1 min followed by an infusion of either 1.0 µg/kg/min or 3.0 µg/kg/min. ASA, aspirin. *TIMI grade 3 flow and corrected TIMI frame count.
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