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Figure 3 Change in left ventricular (LV) end-diastolic dimension (solid bar) and end-systolic dimension (hatched bar) after three months of therapy with carvedilol. **p < 0.002, ****p < 0.0001 compared with baseline. Paired data were obtained in 122 New York Heart Association (NYHA) class I–III patients and 41 class IV patients.