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Figure 3 Progressive narrowing of the lumen of the coronary artery in patient No. 2 after 6 months. Coronary angiogram of the left coronary artery (in left cranial view) shows mild coronary stenosis with a 25% reduction in lumen diameter in the proximal portion after the intracoronary administration of isosorbid. Occlusive vasospasm was found at the same site at that time (upper). Six months later, rapid progression from a 25% to a 90% fixed coronary stenosis was observed at the previously spastic segment after the intracoronary administration of isosorbide in the follow-up angiogram (lower).
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