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Figure 1 (A) Change after 12 weeks of treatment in exercise duration (s) in the four groups. *p < 0.05 vs. placebo; #p < 0.05 vs. 2.5-mg imidapril. A significant dose-response relation was observed by the linear trend test (p = 0.019). (B) Change after 12 weeks of treatment in physical (or pulse) working capacity (PWC) in watts at a heart rate of 110 beats/min (PWC110). *p < 0.05 vs. placebo. There was also a significant dose-response effect (p < 0.05).





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