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Figure 2 Effect of candesartan on infarct size. Infarct size in percent of the area at risk was significantly reduced in the pigs receiving candesartan (filled bars) as compared to that of the placebo group (open bars) (p < 0.05 vs. placebo). In the relationships between infarct size and subendocardial blood flow, subendocardial blood flow in the area at risk correlated inversely to infarct size in the placebo (open squares) and the candesartan group (filled squares). Infarct size for any given subendocardial blood flow was significantly reduced in the candesartan group.
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