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Figure 1 Incidence of VES during 40 min of separate perfusion and an additional 40 min of serial perfusion in NZW (n = 12) and WHHL (n = 8) rabbits. During serial perfusion, isolated hearts are perfused with the effluent of the same animal’s isolated lung. To exclude flow-dependency of arrhythmias, mechanical flow reduction (i.e., volume-controlled perfusion) comparable to the effects seen during serial perfusion was performed in isolated NZW and WHHL hearts (M-NZW, New Zealand mechanical flow reduction group; M-WHHL, Watanabe mechanical flow reduction group, n = 6 for both groups). ##, p < 0.01 vs. separate perfusion.





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