Please click here to obtain permission to reproduce this image.
Click on image to view larger version.
Figure 3 The efficacy of nicorandil and verapamil on nonsustained VTs. (Top) Time course of couplets and nonsustained VTs in five patients who had nicorandil-sensitive nonsustained VT. The arrhythmias were reduced significantly by nicorandil (before nicorandil: 141 ± 99 in 10 min; after nicorandil: 34 ± 40 in 10 min; p < 0.05), and then reappeared 30 min later (68 ± 62 in 10 min). The arrhythmias were reduced again after verapamil (4 ± 4 in 10 min). (Bottom) Percentage of inhibition of the arrhythmias by drugs. Verapamil suppressed >50% of the arrhythmias in four of four patients with nicorandil-sensitive nonsustained VT who were tested. One VT (patient H.T.) was not suppressed by nicorandil and verapamil, although ATP suppressed it.
|
