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Figure 2 The effects of dobutamine on heart rate (A), stroke volume (B) and cardiac output (C). Control data are shown in open bars and stenosis in shaded bars. Statistical significance vs. baseline (dobutamine = 0) within each group (control or stenosis) is indicated by: # = p < 0.05; ## = p < 0.01. Significant differences between control and stenosis at each dobutamine level are indicated by: * = p < 0.05; ** = p < 0.01. Note that the indexed stroke volume (SVIND) and cardiac output (COIND) were determined at a fixed preload (end-diastolic volume). If the changes in preload had not been taken into account, the differences between control and stenosis would have been less pronounced. For details see text and Table 1.
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