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Figure 5 Autoradiograms of midventricular slices of hearts subjected to 1 h of coronary occlusion and reperfusion. 123I-GdDTPA-albumin was injected either before reperfusion (A), at (B), at 1 (C) or at 24 h (D) after reperfusion. The accumulation of labeled albumin in the anterolateral wall of the left ventricle indicates vascular injury. Maximal and essentially homogeneous accumulation of labeled albumin occurs when administered before reperfusion (A). When 123I-GdDTPA-albumin was administered later during reperfusion, less indicator was observed in the infarct core (D, arrowheads).





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