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Figure 2 The frequency of treatment failure is shown for the four therapeutic groups. Patients randomized to triple therapy were significantly less likely to fail compared to any of the other three groups. Treatment failure did not differ significantly between double therapy arms. ACEI + Diur = ACEI and diuretic, Dig + Diur = digoxin and diuretic, Diur = diuretic, triple = digoxin, diuretic and ACEI. *p < 0.01 compared to all other groups.





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