Comparison
|
Odds Ratio (95% Confidence Interval)
|
Chi-square
|
p
|
|
| Any atenolol vs. no atenolol |
|
|
|
| Unadjusted |
0.20 (0.19–0.22) |
1,600 |
< 0.0001 |
| Including only "atenolol-eligible"* |
0.29 (0.26–0.32) |
441 |
< 0.0001 |
| Adjusted |
0.33 (0.31–0.36) |
616 |
< 0.0001 |
| Adjusted, removing deaths within 24 h |
0.48 (0.43–0.54) |
161 |
< 0.0001 |
| Adjusted, removing deaths within 48 h |
0.53 (0.46–0.60) |
95 |
< 0.0001 |
| Any intravenous atenolol vs. no atenolol |
|
|
|
| Unadjusted |
0.50 (0.46–0.54) |
287 |
0.0001 |
| Including only "atenolol-eligible"* |
0.64 (0.57–0.71) |
63 |
0.0001 |
| Adjusted |
0.71 (0.65–0.78) |
58 |
0.0001 |
| Oral atenolol alone vs. no atenolol |
|
|
|
| Unadjusted |
0.14 (0.14–0.16) |
1,395 |
< 0.0001 |
| Including only "atenolol-eligible"* |
0.22 (0.19–0.26) |
403 |
< 0.0001 |
| Adjusted |
0.22 (0.19–0.25) |
650 |
< 0.0001 |
| Adjusted, removing deaths within 24 h |
0.34 (0.29–0.40) |
202 |
< 0.0001 |
| Adjusted, removing deaths within 48 h |
0.39 (0.33–0.47) |
121 |
< 0.0001 |
| Intravenous and oral atenolol vs. oral atenolol alone |
|
|
|
| Unadjusted |
1.2 (1.0–1.3) |
5 |
0.03 |
| Adjusted |
1.2 (1.1–1.5) |
15 |
0.0001 |
| Adjusted, removing deaths within 24 h |
1.3 (1.1–1.6) |
10 |
0.001 |
| Adjusted, removing deaths within 48 h |
1.3 (1.0–1.5) |
5 |
0.02 |
| Adjusted, removing deaths within 48 h, and including only patients first given oral atenolol on day 1 (n = 15,171) |
1.1 (0.87–1.4) |
0.6 |
0.4 |
| Adjusted, removing patients developing shock within 48 h (n = 28,273) |
1.1 (0.95–1.4) |
9.7 |
0.002 |
Adjusted, including only patients first given oral atenolol on day 1 or 2 (n = 22,790)
|
1.3 (1.1–1.5)
|
2.0
|
0.15
|
