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Figure 3 A) Inotropic response to 3.0 mmol/L Ca2+ concentration. Percent baseline developed force (%BDF) versus age group (senior, >60 years; junior, ≤60 years) is depicted. Increase in developed force after exposure to exogenous Ca2+ did not differ between senior and junior myocardium (p > 0.05). B) Maximum rate of systolic contraction after Ca2+ bolus (as measured by the ratio of +dF/dt before and after Ca2+ bolus) was increased in the younger patients; however, older patients were not able to increase their rates of systolic contraction. C) Maximum rate of diastolic relaxation or compliance after Ca2+ bolus (as measured by the ratio of –dF/dt before and after Ca2+ bolus) was increased in the younger patients; however, older patients were not able to increase their rates of diastolic relaxation. Dotted lines depict the 95% confidence limits.





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