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J Am Coll Cardiol, 2010; 55:432-440, doi:10.1016/j.jacc.2009.10.014 (Published online 25 November 2009).
© 2009 by the American College of Cardiology Foundation
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Randomized Comparison of Percutaneous Coronary Intervention With Coronary Artery Bypass Grafting in Diabetic Patients

1-Year Results of the CARDia (Coronary Artery Revascularization in Diabetes) Trial

Akhil Kapur, MBChB, MD*, Roger J. Hall, MD{dagger},{ddagger}, Iqbal S. Malik, MMBChir, PhD{dagger}, Ayesha C. Qureshi, MBBS*, Jeremy Butts, MBBS{dagger}, Mark de Belder, MD§, Andreas Baumbach, MS||, Gianni Angelini, MD, MCh||, Adam de Belder, MBBS, MD, Keith G. Oldroyd, MBChB, MD#, Marcus Flather, MBBS{dagger},**, Michael Roughton, MSc**, Petros Nihoyannopoulos, MD{dagger}, Jens Peder Bagger, MBBS, DSc{dagger}, Kenneth Morgan, MBChB, BSc{dagger} and Kevin J. Beatt, MBBS, PhD{dagger}{dagger},*

* London Chest Hospital, Barts and The London NHS Trust, London, England
{dagger} Imperial College Healthcare NHS Trust, London, England
{ddagger} Norfolk and Norwich University Hospitals, Norwich, England
§ James Cook University Hospital, Middlesbrough, England
|| Bristol Heart Institute, Bristol, England
Royal Sussex County Hospital, Brighton, England
# Western Infirmary, Glasgow, Scotland
** Royal Brompton and Harefield NHS Foundation Trust, London, England
{dagger}{dagger} Mayday University Hospital, London, England


Figure 1
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Figure 1 Patient Enrollment and Follow-Up

*These patients are included in the 1-year follow-up. CABG = coronary artery bypass grafting; PCI = percutaneous coronary intervention.

 

Figure 2
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Figure 2 Primary End Point Event-Free Survival CABG Versus PCI and MACCE Event-Free Survival CABG Versus PCI

Shown are the 1-year Kaplan-Meier event-free survival curves for CABG (blue line) and PCI (orange line) for the primary outcome of death, myocardial infarction (MI), or stroke (A) and death, MI, stroke, or repeat revascularization (revasc) (major adverse coronary and cerebral events [MACCE]) (B). Hazard ratios and 95% confidence intervals for these comparisons are provided in Table 2. Abbreviations as in Figure 1.

 

Figure 3
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Figure 3 Forest Plot of Death, Myocardial Infarction, and Stroke in Key Subgroups

Squares represent point estimates for the hazard ratio (HR) and horizontal lines represent 95% confidence interval (CI). Arrows indicate that the upper limit of HR goes off the log scale. Also see Table 3. BMS = bare-metal stent(s); DES = drug-eluting stent(s); other abbreviations as in Figure 1.

 




 
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