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J Am Coll Cardiol, 2010; 55:221-230, doi:10.1016/j.jacc.2009.09.022 (Published online 11 November 2009).
© 2009 by the American College of Cardiology Foundation
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Normal Stress-Only Versus Standard Stress/Rest Myocardial Perfusion Imaging

Similar Patient Mortality With Reduced Radiation Exposure

Su Min Chang, MD*, Faisal Nabi, MD*, Jiaqiong Xu, PhD{dagger}, Umara Raza, MD* and John J. Mahmarian, MD*,*

* Methodist DeBakey Heart and Vascular Center
{dagger} Methodist Hospital Research Institute, The Methodist Hospital, Houston, Texas


Figure 1
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Figure 1 Survival for the Entire Cohort According to SPECT Protocol

Survival curves for the entire cohort according to single-photon emission computed tomographic myocardial perfusion imaging (SPECT) protocol on the basis of whether patients with a normal SPECT had stress-only versus additional rest imaging (A) or stress-only versus stress-rest or rest-stress imaging (B).

 

Figure 2
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Figure 2 Survival on the Basis of Sex for Each SPECT Protocol

Survival curves on the basis of female (A) or male (B) sex for each single-photon emission computed tomographic myocardial perfusion imaging (SPECT) protocol.

 

Figure 3
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Figure 3 Survival on the Basis of Diabetic Status for Each SPECT Protocol

Survival curves on the basis of the presence (A) or absence (B) of diabetes mellitus for each single-photon emission computed tomographic myocardial perfusion imaging (SPECT) protocol. Diabetic persons had a significantly higher mortality rate than nondiabetic persons, but death rates were similar in the 2 imaging protocols.

 

Figure 4
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Figure 4 Survival on the Basis of CAD Status for Each SPECT Protocol

Survival curves on the basis of the presence (A) or absence (B) of coronary artery disease (CAD) for each single-photon emission computed tomographic myocardial perfusion imaging (SPECT) protocol. Patients with CAD had a higher mortality rate than non-CAD patients, irrespective of the imaging protocol used to evaluate them.

 

Figure 5
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Figure 5 Survival on the Basis of Stressor Modality for Each SPECT Protocol

Survival curves on the basis of the stressor modality used for each single-photon emission computed tomographic myocardial perfusion imaging (SPECT) protocol. Patients undergoing treadmill exercise (A) had a significantly lower mortality than those who had pharmacologic stress testing (B). However, within both groups, mortality rates were similar among the 2 imaging protocols.

 

Figure 6
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Figure 6 Survival on the Basis of Duke Treadmill Score for Each SPECT Protocol

Survival curves on the basis of a low (A) or intermediate (B) risk Duke Treadmill score for each single-photon emission computed tomographic myocardial perfusion imaging (SPECT) protocol. Patients with a low-risk Duke Treadmill Score had a significantly lower mortality rate than those with an intermediate-risk score, irrespective of the imaging protocol they received.

 




 
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