The Everolimus-Eluting Stent in Real-World PatientsSix-Month Follow-Up of the Xience V Stent Evaluated at Rotterdam Cardiac Hospital (X-SEARCH) Registry
Yoshinobu Onuma, MD,
Neville Kukreja, MA, MRCP,
Nicolo Piazza, MD,
Jannet Eindhoven, MSc,
Chrysafios Girasis, MD,
Lisanne Schenkeveld, MSc,
Ron van Domburg, PhD,
Patrick W. Serruys, MD, PhD* Interventional Cardiologists of the Thoraxcenter (2000 to 2007)
Thoraxcenter, Erasmus Medical Center, Rotterdam, the Netherlands
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Figure 1 Flowchart of Patient Selection
The flowchart represents patient inclusion and exclusion in the X-SEARCH (Xience Stent Evaluated At Rotterdam Cardiology Hospital) registry. *Occurring in the short transitional period (2 weeks) between paclitaxel-eluting stent/everolimus-eluting stent. BMS = bare-metal stent; DES = drug-eluting stent(s); PCI = percutaneous coronary intervention.
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Figure 2 Inclusion Periods of X-SEARCH and Historical Cohorts
Chronological order of 4 cohorts included in analysis: BMS, everolimus-eluting stent (EES), paclitaxel-eluting stent (PES), and SES. X-SEARCH = Xience Stent Evaluated At Rotterdam Cardiology Hospital; other abbreviations as in Figure 1.
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Figure 3 Unadjusted Survival Curves
Kaplan-Meier survival curves stratified according to the stent types: (A) all-cause death; (B) the composite of death or myocardial infarction; (C) target vessel revascularization; and (D) the composite of major adverse cardiac events (all-cause mortality, any myocardial infarction, or target vessel revascularization). BMS (black lines); EES (green lines); PES (yellow lines); SES (red lines). Abbreviations as in Figures 1 and 2.
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Figure 4 Adjusted Survival Curves
Adjusted survival curves stratified according to the stent types using Cox proportional hazard model: (A) all-cause death; (B) the composite of death or myocardial infarction; (C) target vessel revascularization; and (D) the composite of major adverse cardiac events (all-cause mortality, any myocardial infarction, or target vessel revascularization). BMS (black lines); EES (green lines); PES (yellow lines); SES (red lines). Abbreviations as in Figures 1 and 2.
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