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Treatment of Obstructive Sleep Apnea Is Associated With Decreased Cardiac Death After Percutaneous Coronary Intervention

Andrew Cassar, MD, MRCP^_*, Timothy I. Morgenthaler, MD, FCCP, Ryan J. Lennon, MS, Charanjit S. Rihal, MD, FACC and Amir Lerman, MD, FACC^,_*

^_* Department of Internal MedicineMayo College of Medicine, Rochester, Minnesota
Division of Pulmonary and Critical CareMayo College of Medicine, Rochester, Minnesota
Division of BiostatisticsMayo College of Medicine, Rochester, Minnesota
Division of Cardiovascular Disease, Mayo College of Medicine, Rochester, Minnesota

View larger version (18K): [in this window] [in a new window] [Download PPT slide]   Figure 1 Study Cohort Profile AHI = apnea-hypoxia index; OSA = obstructive sleep apnea; PCI = percutaneous coronary intervention; PSG = polysomnography.

View larger version (16K): [in this window] [in a new window] [Download PPT slide]   Figure 2 Kaplan-Meier Estimates of Cardiac Death After PCI Treatment of OSA was associated with a significantly lower incidence of cardiac death after PCI (p = 0.027 by log-rank test). Abbreviations as in Figure 1.

View larger version (17K): [in this window] [in a new window] [Download PPT slide]   Figure 3 Kaplan-Meier Estimates of All-Cause Mortality After PCI A lower incidence of death after PCI in those treated for OSA was nearly statistically significant (p = 0.058 by log-rank test). Abbreviations as in Figure 1.