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Surgical Myectomy Versus Alcohol Septal Ablation for Obstructive Hypertrophic Cardiomyopathy

Will There Ever Be a Randomized Trial?

Iacopo Olivotto, MD^_*,_*, Steve R. Ommen, MD, Martin S. Maron, MD, Franco Cecchi, MD^_* and Barry J. Maron, MD

^_* Referral Center for Myocardial Diseases, Department of Cardiology, Azienda Ospedaliera Universitaria Careggi, Florence, Italy
Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota
Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota
Cardiology Division, Tufts–New England Medical Center, Boston, Massachusetts

View larger version (71K): [in this window] [in a new window] [Download PPT slide]   Figure 1 Estimates for a Theoretical Surgical Myectomy Versus ASA Trial Flow diagrams comparing patient selection and recruitment in the BARI study (coronary artery bypass graft surgery [CABG] vs. percutaneous transluminal coronary angioplasty [PTCA]): a representative example of a coronary artery disease-related randomized trial (23) (left) and a hypothetical myectomy versus alcohol septal ablation (ASA) trial (right). HCM = hypertrophic cardiomyopathy.