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The Role of Coenzyme Q10 in Statin-Associated Myopathy

A Systematic Review

Leo Marcoff, MD^_* and Paul D. Thompson, MD^,,_*

^_* Section of Cardiology, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut
Hartford Hospital, Hartford, Connecticut
University of Connecticut, Farmington, Connecticut

View larger version (18K): [in this window] [in a new window] [Download PPT slide]   Figure 1 Products of Mevalonate Pathway Possibly Affected by HMG-CoA Reductase Inhibitors (Statins) Reprinted with permission from Thompson et al. (2). Copyright American Medical Association ©2003. All rights reserved. HMG-CoA = 3-hydroxy-3-methylglutaryl coenzyme A.