Central Sleep Apnea, Right Ventricular Dysfunction, and Low Diastolic Blood Pressure Are Predictors of Mortality in Systolic Heart Failure
Shahrokh Javaheri, MD*,
Rakesh Shukla, PhD,
Haoyue Zeigler, MS and
Laura Wexler, MD
Department of Veterans Affairs Medical Center, Cincinnati, Ohio; and the Departments of Medicine and Environmental Health, University of Cincinnati College of Medicine, Cincinnati, Ohio. This work was supported by grants from the Merit Review Program
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Figure 1 CSA is a Predictor of Mortality in Systolic HF
Survival of heart failure (HF) patients with or without central sleep apnea (CSA) after accounting for all other confounders. AHI = apnea-hypopnea index.
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Figure 2 Median Survival of Heart Failure Patients Using Different AHI Cutoff Points
Survival was shorter in patients with more severe central sleep apnea than those who had less severe disorder. This is true for all categories. The p values show significance comparing the median survival. The respective hazard ratios: 2.14, p = 0.02; 2.13, p = 0.01; 1.76, p = 0.047; 1.93, p = 0.02; 1.85, p = 0.03; and 1.84, p = 0.04. AHI = apnea-hypopnea index.
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