Characteristics, Management, and Outcomes of 5,557 Patients Age  90 Years With Acute Coronary SyndromesResults From the CRUSADE Initiative
Adam H. Skolnick, MD*,
Karen P. Alexander, MD ,
Anita Y. Chen, MS,
Matthew T. Roe, MD, MSH,
Charles V. Pollack, Jr, MD, MA ,
E. Magnus Ohman, MD,
John S. Rumsfeld, MD, PhD ,
W. Brian Gibler, MD||,
Eric D. Peterson, MD, MPH and
David J. Cohen, MD, MSc*,¶,*
* Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts
Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina
Pennsylvania Hospital, University of Pennsylvania Health System, Philadelphia, Pennsylvania
Denver VA Medical Center/University of Colorado, Denver, Colorado
|| University of Cincinnati College of Medicine, Cincinnati, Ohio
¶ Saint Luke's Mid America Heart Institute, Kansas City, Missouri
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Figure 1 Relationship Between In-Hospital Mortality Across Each Age Group With Increasing Adherence to Recommended Therapies
Guideline-recommended therapies included acute (<24 h) aspirin, acute beta-blockers, acute heparin and cardiac catheterization within 48 h, and receipt of glycoprotein IIb/IIIa inhibitors for patients undergoing early catheterization. Patients who were transferred out were excluded from this analysis.
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Figure 2 Relationship Between the Number of Therapies Provided and the Incidence of In-Hospital Major Bleeding in Each Group, Including Only the "Ideal Patient Cohort"
Therapies considered included acute (<24 h) aspirin, acute heparin, acute clopidogrel, and catheterization within 48 h with or without the use of glycoprotein IIb/IIIa inhibitors. Patients who were transferred out or who underwent coronary artery bypass surgery during the hospitalization were excluded from this analysis.
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