Early Prediction of Infarct Size by Strain Doppler Echocardiography After Coronary Reperfusion
Trond Vartdal, MD*,
Harald Brunvand, MD, PhD*,
Eirik Pettersen, MD*,
Hans-Jørgen Smith, MD, PhD ,
Erik Lyseggen, MD, PhD*,
Thomas Helle-Valle, MD*,
Helge Skulstad, MD, PhD*,
Halfdan Ihlen, MD, PhD* and
Thor Edvardsen, MD, PhD*,*
* Department of Cardiology
Department of Radiology, Rikshospitalet University Hospital, University of Oslo, Oslo, Norway. Drs. Vartdal, Lyseggen, and Helle-Valle were recipients of a clinical research fellowship from the Norwegian Council on Cardiovascular Diseases, and Dr. Pettersen was a recipient of a clinical research fellowship from the Norwegian Research Council
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Figure 1 Example of Strain Curves in Infarcted and Remote Areas
Myocardial strain assessed in the acute phase compared with the myocardial scarring 9 months later (middle panel). At left, dyskinesia is shown in the infarcted area with systolic lengthening of the myocardium, followed by postsystolic shortening. A normal strain curve from the noninfarcted remote area with systolic shortening and diastolic lengthening is shown at right. Arrows indicate the peak negative strain values. MRI = magnetic resonance imaging.
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Figure 2 Transmural Extent of Infarction Measured by Strain
The transmural extent of delayed enhancement in myocardial segment is inversely related to a decrease in absolute strain values.
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Figure 3 Correlation Between the Global Peak Negative Strain and MRI
The correlation between the global peak negative strain value in each patient and infarct size by magnetic resonance imaging (MRI) calculated as percentage of total volume is shown.
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