Arterial Ultrasonography and Tonometry as Adjuncts to Cardiovascular Risk Stratification
Iftikhar J. Kullo, MD, FACC* and
A. Rauoof Malik, MD
Division of Cardiovascular Diseases, Mayo Clinic and Foundation, Rochester, Minnesota
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Figure 1 Association of Altered Arterial Function and Structure With Cardiovascular Events
Functional and structural abnormalities in the arterial wall caused by conventional, novel, and genetic risk factors promote the development of atherosclerotic plaque. Functional abnormalities in the arterial wall may favor progression of nonobstructive plaques to more advanced, flow-limiting lesions. Additionally, such changes may increase the propensity of atherosclerotic plaque to fissuring and rupture, thereby precipitating acute cardiovascular events.
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Figure 2 A Proposed Algorithm Incorporating Arterial Testing in the Primary Prevention Setting
Arterial ultrasonography and tonometry may be useful in refining estimates of coronary heart disease (CHD) risk in intermediate-risk and select low-risk individuals.
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