Effects of Intravenous Atrial Natriuretic Peptide on Cardiac Sympathetic Nerve Activity and Left Ventricular Remodeling in Patients With First Anterior Acute Myocardial Infarction
Shu Kasama, MD*,*,
Takuji Toyama, MD*,
Takashi Hatori, MD*,
Hiroyuki Sumino, MD*,
Hisao Kumakura, MD ,
Yoshiaki Takayama, MD,
Shuichi Ichikawa, MD,
Tadashi Suzuki, MD* and
Masahiko Kurabayashi, MD*
* Department of Cardiovascular Medicine, Gunma University School of Medicine, Maebashi, Japan
Department of Internal Medicine, Cardiovascular Hospital of Central Japan, Gunma, Japan
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Figure 1 Comparison of Cardiac 123I-Meta-Iodobenzylguanidine Scintigraphic Findings 3 Weeks After Treatment
H/M = heart/mediastinum count; TDS = total defect score; WR = washout rate. *p < 0.05 compared with group A; p < 0.005 compared with group A.
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Figure 2 Representative Single-Photon Emission Computerized Tomographic MIBG Images 3 Weeks After Treatment for Both Groups
ANP = atrial natriuretic peptide; HLA = horizontal long axis; ISDN = isosorbide dinitrate; MIBG = 123I-meta-Iodobenzylguanidine; SA = short axis; VLA = vertical long axis.
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Figure 3 Representative Anterior Planar Delayed MIBG Images 3 Weeks After Treatment for Both Groups
In these 2 examples, delayed heart/mediastinum (H/M) count ratio and washout rate were 2.01 and 36%, respectively, for a patient from group A and 1.55 and 52%, respectively, for a patient from group B. Abbreviations as in Figure 2.
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