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Myocardial Scars More Frequent Than Expected

Magnetic Resonance Imaging Detects Potential Risk Group

Charlotte Ebeling Barbier, MD^_*,_*, Tomas Bjerner, MD, PhD^_*, Lars Johansson, PhD^_*,, Lars Lind, MD, PhD^, and Håkan Ahlström, MD, PhD^_*

^_* Department of Radiology, Uppsala University Hospital, Uppsala, Sweden
AstraZeneca, Gothenburg, Sweden
Department of Medicine, Uppsala University Hospital, Uppsala, Sweden

View larger version (13K): [in a new window]   Figure 1 Groups were formed from the population-based sample of 70-year-old subjects. MRI = magnetic resonance imaging; No MI = no myocardial infarction scar; RMI = recognized myocardial infarction (i.e., MI scar in combination with MI diagnosis in medical records); UMI = unrecognized myocardial infarction.

View larger version (79K): [in a new window]   Figure 2 Short-axis magnetic resonance images from 10 consecutive subjects displaying previously unrecognized myocardial infarctions. Note that these myocardial infarction scars were visible in the same location in both short and long axis and that some involve the subendocardial layer in another slice than the one displayed.

View larger version (10K): [in a new window]   Figure 3 The distribution of unrecognized (A) and recognized (B) myocardial infarction scars between the 17 segments of the American Heart Association segmentation.

View larger version (13K): [in a new window]   Figure 4 Differences in ejection fraction (EF) and in left ventricular (LV) mass adjusted for body surface area (BSA) and gender between the subjects without myocardial infarction scars (No MI), those with unrecognized myocardial infarction (UMI), and those with recognized myocardial infarction (RMI). *p < 0.0167 (i.e., 0.05 with Bonferroni correction).