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The Potential of Myocardial Perfusion Scintigraphy for Risk Stratification of Asymptomatic Patients With Type 2 Diabetes

Jeroen J. Bax, MD^_*,_*, Robert O. Bonow, MD, Diethelm Tschöpe, MD, Silvio E. Inzucchi, MD, Eugene Barrett, MD^|| Global Dialogue Group for the Evaluation of Cardiovascular Risk in Patients With Diabetes

^_* Leiden University Medical Center, Leiden, the Netherlands
University Hospital of the Ruhr-University Bochum, Bad Oeynhausen, Germany
Northwestern University Feinberg School of Medicine, Chicago, Illinois
Yale University School of Medicine, New Haven, Connecticut
^|| University of Virginia, Charlottesville, Virginia

View larger version (10K): [in a new window]   Figure 1 Diabetes confers the same risk of myocardial infarction (MI) in a patient without history of MI as a prior MI in a nondiabetic patient. Data are from an observational study of 1,373 nondiabetic subjects and 1,059 diabetic subjects in Finland after 8 years of follow-up. On the basis of data presented by Haffner et al. (3).

View larger version (14K): [in a new window]   Figure 2 Prevalence and characteristics of abnormal single-photon emission computed tomography scans in diabetic patients without evidence of coronary artery disease: data from the DIAD (Detection of Silent Myocardial Ischemia in Asymptomatic Diabetics) study. On the basis of data presented by Wackers et al. (10).

View larger version (19K): [in a new window]   Figure 3 Potential algorithm on the implementation of myocardial perfusion imaging (MPS) in risk stratification of diabetic patients without symptoms of coronary artery disease.