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Metabolic Syndrome and Early-Onset Coronary Artery Disease

Is the Whole Greater Than Its Parts?

Carlos Iribarren, MD, MPH, PhD^_*,,_*, Alan S. Go, MD^_*,, Gail Husson, MPH, Med^_*, Stephen Sidney, MD, MPH^_*, Joan M. Fair, ANP, PhD, Thomas Quertermous, MD, Mark A. Hlatky, MD^,|| and Stephen P. Fortmann, MD

^_* Kaiser Permanente Division of Research, Oakland, California
Departments of Epidemiology, Biostatistics, and Medicine, University of California, San Francisco, California
Stanford Prevention Research Center
Division of Cardiovascular Medicine
^|| Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California

View larger version (14K): [in this window] [in a new window] [Download PPT slide]   Figure 1 Early-onset coronary artery disease (CAD) definition criteria in the ADVANCE Study. CABG = coronary artery bypass graft; CK-MB = creatine kinase-MB fraction; CPT = current procedural terminology; EKG = electrocardiogram; ICD-9 = ninth revision of the International Classification of Diseases; MD = metabolic syndrome; PCI = percutaneous coronary intervention.

View larger version (20K): [in this window] [in a new window] [Download PPT slide]   Figure 2 Schematic representation of the recruitment process for early-onset coronary artery disease subjects in the ADVANCE study. PCP = primary care provider. *Numbers do not add up because electronic exclusions are not mutually exclusive.