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Clinical Outcomes for Sirolimus-Eluting Stents and Polymer-Coated Paclitaxel-Eluting Stents in Daily Practice

Results From a Large Multicenter Registry

Francesco Saia, MD, PhD^_*,_*, Giancarlo Piovaccari, MD, Antonio Manari, MD, Andrea Santarelli, MD, Alberto Benassi, MD, Enrico Aurier, MD^||, Pietro Sangiorgio, MD^¶, Fabio Tarantino, MD^#, Giuseppe Geraci, MD^_**, Giuseppe Vecchi, MD, Paolo Guastaroba, MSc, Roberto Grilli, MD and Antonio Marzocchi, MD^_*

^_* Istituto di Cardiologia, Università di Bologna, Policlinico S. Orsola-Malpighi, Bologna, Italy
Unità Operativa di Cardiologia, Ospedale degli Infermi, Rimini, Italy
Unità Operativa di Cardiologia Interventistica, Ospedale S. Maria Nuova, Reggio Emilia, Italy
Laboratorio di Emodinamica, Hesperia Hospital, Modena, Italy
^|| Divisione di Cardiologia, Ospedale Maggiore, Parma, Italy
^¶ Divisione di Cardiologia, Ospedale Maggiore, Bologna, Italy
^# Laboratorio di Emodinamica, Ospedale Morgagni, Forlì, Italy
^_** Laboratorio di Emodinamica, Policlinico di Modena, Modena, Italy
Unità Operativa di Cardiologia—Centro Interventistico, Ospedale S. Maria delle Croci, Ravenna, Italy
Agenzia Sanitaria Regionale Regione Emilia-Romagna, Bologna, Italy

View larger version (10K): [in a new window]   Figure 1 Propensity score-adjusted cumulative incidence of (A) death and acute myocardial infarction (AMI), (B) target vessel revascularization (TVR), and (C) major adverse cardiac events (MACE) in the paclitaxel-eluting stent (PES) and in the sirolimus-eluting stent (SES) groups. CI = confidence interval.

View larger version (21K): [in a new window]   Figure 2 Hazard ratio of 1-year target vessel revascularization (Cox proportional hazards models) in subgroups of patients according to clinical and angiographic characteristics. AMI = actue myocardial infarction; CI = confidence interval; HR = hazard ratio; LAD = left anterior descending coronary artery; NQWMI = non–Q-wave myocardial infarction; PCI = percutaneous coronary intervention.