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Circulating Endothelial Cells in Cardiovascular Disease

Haemostasis, Thrombosis, and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, United Kingdom

View larger version (94K): [in a new window]   Figure 1 A circulating endothelial cell (stained bright green with Ulex europaeus lectin) forming a rosette with at least 10 immunomagnetic beads. Photomicrograph in epifluorescence (Zeiss), wet preparation, magnification x40. For scale, the large number of residual immunomagnetic beads each have a diameter of 4.5 µm.

View larger version (15K): [in a new window]   Figure 2 Relationship of von Willebrand factor (vWf) and circulating endothelial cells (CECs) in heart failure. Spearman correlation, r = 0.463; p < 0.0001. Reprinted, with permission, from Chong et al. (37).

View larger version (18K): [in a new window]   Figure 3 Simplified discrimination of endothelial progenitor cells from circulation endothelial cells. CEC = circulating endothelial cell, EC = mural endothelial cell, EPC = endothelial progenitor cell.