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Young Adult Myocardial Infarction and Ischemic Stroke

The Role of Paradoxical Embolism and Thrombophilia (The YAMIS Study)

Sanjay Sastry, MBChB, MRCP^_*, Graham Riding, FRCS^_*, Julie Morris, MSc, David Taberner, FRCP, FRCPath, Nicola Cherry, MD, PhD, FRCP, Anthony Heagerty, MD, FRCP, FMedSci^|| and Charles McCollum, FRCS, MD^_*,_*

^_* Academic Surgery Unit, South Manchester University Hospital, Manchester, United Kingdom
Department of Medical Statistics, South Manchester University Hospital, Manchester, United Kingdom
Thrombosis Reference Centre, South Manchester University Hospital, Manchester, United Kingdom
^|| Department of Medicine, Manchester Royal Infirmary, Manchester, United Kingdom
Department of Public Health Sciences, University of Alberta, Edmonton, Alberta, Canada

View larger version (160K): [in a new window]   Figure 1 Characteristic appearance of microbubbles on a middle cerebral artery Doppler trace in a patient with a venous-to-arterial circulation shunt.