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Metyrapone Improves Endothelial Dysfunction in Patients With Treated Depression

Andrew J.M. Broadley, MRCP^_*, Ania Korszun, MRCPsych, Eltigani Abdelaal, MRCP^_*, Valentina Moskvina, PhD, John Deanfield, FRCP, Christopher J.H. Jones, FRCP and Michael P. Frenneaux, FRCP, FACC^_*,_*

^_* Department of Cardiovascular Medicine, University of Birmingham, Birmingham, England
Department of Psychological Medicine, St. Bartholomew's and Royal London Hospital School of Medicine, London, England
Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, Wales
Department of Cardiology, Great Ormond Street Hospital for Children, London, England

View larger version (11K): [in a new window]   Figure 1 Brachial artery diameter change over time profiles: patients and control subjects (morning flow-mediated dilation).

View larger version (9K): [in a new window]   Figure 2 Change in flow-mediated dilation (FMD) after placebo/metyrapone.