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J Am Coll Cardiol, 2006; 47:921-929, doi:10.1016/j.jacc.2005.09.065 (Published online 8 February 2006).
© 2006 by the American College of Cardiology Foundation
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Peripheral Arterial Disease in Patients With Diabetes

Steven P. Marso, MD, FACC*,* and William R. Hiatt, MD{dagger}

* Mid America Heart Institute, University of Missouri-Kansas City, Saint Luke's Hospital, Kansas City, Missouri
{dagger} Divisions of Geriatrics and Cardiology, Section of Vascular Medicine, University of Colorado Health Sciences Center and the Colorado Prevention Center, Denver, Colorado


Figure 1
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  		Figure 1 Typical protocol for the diagnosis of peripheral arterial disease in patients with diabetes. Reprinted with permission from N Engl J Med 2001;344:1608–21. Copyright © 2001 Massachusetts Medical Society. All rights reserved. ABI = ankle-brachial index; PAD = peripheral arterial disease; PVR = pulse-volume recording; UDS = ultrasonic duplex scanning.

 

Figure 2
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  		Figure 2 Relative-risk reduction and 95% confidence interval by disease subgroup in the Clopidogrel versus Aspirin in Patients at Risk of Ischemic Events (CAPRIE) trial. MI = myocardial infarction; PAD = peripheral arterial disease. Reprinted with permission from Elsevier (Lancet 1996;348:1329–39).

 

Figure 3
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  		Figure 3 The mean maximal walking distance increase from baseline in patients with peripheral arterial disease after 24 weeks of treatment with placebo (n = 239), pentoxifylline 400 mg three times daily (n = 232), or cilostazol 100 mg twice daily (n = 227). *p < 0.001 vs. pentoxifylline (84).

 




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